QEEG To Guide Medication
QEEG to Guide Psychiatric Medication Selection
Quantitative EEG can help guide your physician in determining which medication or combination of
medications will be most helpful with difficulties with attention, mood, anxiety, and behavior, including a
range of psychological or psychiatric disorders. Instead of a lengthy trial and error process, which often
takes many months, and just as often ends with less than satisfactory results, an easy to administer,
scientifically-derived test of your brain's functioning can allow your doctor to select the medication which
has been shown to best restore normal brain function.
Initial studies showed that medication prescription based on indicators from the QEEG resulted in a
significantly higher rate of success than prescription based soley on symptom patterns (as it is usually
done). Additional research has substantially improved the effectiveness of this method, through the
development of a medication-referenced EEG, also known as rEEG
In most areas of medicine, your doctor's decisions are guided by data from scientific laboratory tests. Blood
tests, lab cultures, urine and stool samples - these tests reveal details of your body's functioning which
cannot simply be observed. For most types of disorders, these test are critical to making diagnostic and
treatment decisions. Except for psychological disorders. Brain physiology is not usually tested to guide the
prescription of medications that act on the brain.
With the development of the drug referenced quantitative EEG database (rEEG), it is now possible to guide
treatment decisions for brain-based disorders on a complex and scientifically derived measure of each
individual's brain functioning. Initial research and clinical experience with this important tool have
demonstrated that its use can significantly increase treatment success with a wide range of disorders. This
is especially true for those individuals who have not responded to medications prescribed in the
conventional way.
Referenced-EEG is a patented technology that utilizes digital electroencephalography (EEG) in conjunction
with a normative database and a proprietary clinical (symptomatic) database to identify abnormal patient
physiology. Appropriate medications are then statistically selected specifically to normalize discovered
abnormalities. This process has been correlated to treatment outcome in a database of over 1,600 patients
and 10,000 medication trials. The results of the analysis for each patient are produced in a two-page report
provided to the physician by the reference laboratory.
Multiple studies have shown that treatment guided by rEEG has led to positive outcomes in approximately
80% of the 2000+ patients who have previously failed to respond to traditional treatment efforts.
Coastal Neurotherapy is now making this service available in our region. We will record your EEG in our
center using state of the art QEEG equipment. We then forward the data to the team of physicians who are
responsible for developing this cutting edge neurophysiological lab test.
This enormously data-rich picture of your brain's functioning is then compared to an FDA approved
database of individuals with no known neurological problems. Over one thousand measures of your brain's
function are used by the team to pinpoint the specific pattern of dysfunction that is giving rise to your
difficulties. This pattern is then analyzed against an additional database that links specific underlying
neurological profiles to known constellations of response to a wide range of psychiatric medications.
Armed with this degree of information on brain function and medication response, your chances of rapid
recovery are greatly improved.
This drug referenced qEEG assessment requires that you cease use of all psychiatric medications until
they are no longer active in your system. This allows the acquisition of a "clean" picture of how your brain
functions, without the impact of medications. The consulting psychiatrists at the rEEG lab will work closely
with your prescribing physician on the technical guidelines for this process. This can only be done under
close medical supervision, with the collaboration of your doctor and the rEEG medical staff.
For more information about this assessment procedure, visit www.cnsresponse.com, or call 910-353-1925.
For articles on rEEG from medical publications, go to rEEG helps prescribing or EEG database can help
guide psychotropic Rx
Some of the research using rEEG is listed below:
Suffin SC, Emory WH, Neurometric Subgroups in Attentional and Affective Disorders and Their Association with
Pharmacotherapeutic Outcome. Journal of Clinical Electroencephalography 1995; 26: 76-83.
Stephen C. Suffin, M.D., W. Hamlin Emory, M.D., Nicholas Gutierrez, M.D., Sarla Karan, M.D., Gurdev S. Arora, M.D., Mark
J. Schiller, M.D., Jack Johnston, Ph.D., Arthur Kling, M.D. A QEEG Database Method for Predicting Pharmacotherapeutic
Outcome in Refractory Major Depressive Disorder, in submission.
Suffin SC, Emory WH, Neurometric EEG Classifiers and Response to Medicine. Syllabus and Proceedings Summary,
American Psychiatric Association 1996 Annual Meeting. Washington, DC, 1996; 87-88.
Suffin SC, Gutierrez NM, Karan S, Aurora G, Emory WH, Kling A, Neurometric EEG Predicts Pharmacotherapeutic Outcome
in Depressed Outpatients: A Prospective Trial. Program and Abstracts on New Research, American Psychiatric Association
1997 Annual Meeting. Washington, DC, 1997; 170.
Suffin SC, Emory WH, Proler ML, Neurometric EEG Predictors of Response to Medication in Psychiatric Patients. American
Clinical Neurophysiology Society Program and Proceedings Booklet. Bloomfield, CT,1997; 62.
Emory WH, Schiller M ,Suffin SC, Referenced -EEG in the Treatment of Eating Disorders, presented at 44th Annual
Meeting, NIMH, National Clinical Drug Evaluation Unit, Phoenix, AZ June, 2004.
(http://www.nimh.nih.gov/ncdeu/ncdeu2004abstracts.pdf, Poster No. 221)
Quantitative EEG can help guide your physician in determining which medication or combination of
medications will be most helpful with difficulties with attention, mood, anxiety, and behavior, including a
range of psychological or psychiatric disorders. Instead of a lengthy trial and error process, which often
takes many months, and just as often ends with less than satisfactory results, an easy to administer,
scientifically-derived test of your brain's functioning can allow your doctor to select the medication which
has been shown to best restore normal brain function.
Initial studies showed that medication prescription based on indicators from the QEEG resulted in a
significantly higher rate of success than prescription based soley on symptom patterns (as it is usually
done). Additional research has substantially improved the effectiveness of this method, through the
development of a medication-referenced EEG, also known as rEEG
In most areas of medicine, your doctor's decisions are guided by data from scientific laboratory tests. Blood
tests, lab cultures, urine and stool samples - these tests reveal details of your body's functioning which
cannot simply be observed. For most types of disorders, these test are critical to making diagnostic and
treatment decisions. Except for psychological disorders. Brain physiology is not usually tested to guide the
prescription of medications that act on the brain.
With the development of the drug referenced quantitative EEG database (rEEG), it is now possible to guide
treatment decisions for brain-based disorders on a complex and scientifically derived measure of each
individual's brain functioning. Initial research and clinical experience with this important tool have
demonstrated that its use can significantly increase treatment success with a wide range of disorders. This
is especially true for those individuals who have not responded to medications prescribed in the
conventional way.
Referenced-EEG is a patented technology that utilizes digital electroencephalography (EEG) in conjunction
with a normative database and a proprietary clinical (symptomatic) database to identify abnormal patient
physiology. Appropriate medications are then statistically selected specifically to normalize discovered
abnormalities. This process has been correlated to treatment outcome in a database of over 1,600 patients
and 10,000 medication trials. The results of the analysis for each patient are produced in a two-page report
provided to the physician by the reference laboratory.
Multiple studies have shown that treatment guided by rEEG has led to positive outcomes in approximately
80% of the 2000+ patients who have previously failed to respond to traditional treatment efforts.
Coastal Neurotherapy is now making this service available in our region. We will record your EEG in our
center using state of the art QEEG equipment. We then forward the data to the team of physicians who are
responsible for developing this cutting edge neurophysiological lab test.
This enormously data-rich picture of your brain's functioning is then compared to an FDA approved
database of individuals with no known neurological problems. Over one thousand measures of your brain's
function are used by the team to pinpoint the specific pattern of dysfunction that is giving rise to your
difficulties. This pattern is then analyzed against an additional database that links specific underlying
neurological profiles to known constellations of response to a wide range of psychiatric medications.
Armed with this degree of information on brain function and medication response, your chances of rapid
recovery are greatly improved.
This drug referenced qEEG assessment requires that you cease use of all psychiatric medications until
they are no longer active in your system. This allows the acquisition of a "clean" picture of how your brain
functions, without the impact of medications. The consulting psychiatrists at the rEEG lab will work closely
with your prescribing physician on the technical guidelines for this process. This can only be done under
close medical supervision, with the collaboration of your doctor and the rEEG medical staff.
For more information about this assessment procedure, visit www.cnsresponse.com, or call 910-353-1925.
For articles on rEEG from medical publications, go to rEEG helps prescribing or EEG database can help
guide psychotropic Rx
Some of the research using rEEG is listed below:
Suffin SC, Emory WH, Neurometric Subgroups in Attentional and Affective Disorders and Their Association with
Pharmacotherapeutic Outcome. Journal of Clinical Electroencephalography 1995; 26: 76-83.
Stephen C. Suffin, M.D., W. Hamlin Emory, M.D., Nicholas Gutierrez, M.D., Sarla Karan, M.D., Gurdev S. Arora, M.D., Mark
J. Schiller, M.D., Jack Johnston, Ph.D., Arthur Kling, M.D. A QEEG Database Method for Predicting Pharmacotherapeutic
Outcome in Refractory Major Depressive Disorder, in submission.
Suffin SC, Emory WH, Neurometric EEG Classifiers and Response to Medicine. Syllabus and Proceedings Summary,
American Psychiatric Association 1996 Annual Meeting. Washington, DC, 1996; 87-88.
Suffin SC, Gutierrez NM, Karan S, Aurora G, Emory WH, Kling A, Neurometric EEG Predicts Pharmacotherapeutic Outcome
in Depressed Outpatients: A Prospective Trial. Program and Abstracts on New Research, American Psychiatric Association
1997 Annual Meeting. Washington, DC, 1997; 170.
Suffin SC, Emory WH, Proler ML, Neurometric EEG Predictors of Response to Medication in Psychiatric Patients. American
Clinical Neurophysiology Society Program and Proceedings Booklet. Bloomfield, CT,1997; 62.
Emory WH, Schiller M ,Suffin SC, Referenced -EEG in the Treatment of Eating Disorders, presented at 44th Annual
Meeting, NIMH, National Clinical Drug Evaluation Unit, Phoenix, AZ June, 2004.
(http://www.nimh.nih.gov/ncdeu/ncdeu2004abstracts.pdf, Poster No. 221)
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